Association ofCTLA4 polymorphism with regulatory T cell frequency
نویسندگان
چکیده
منابع مشابه
T-cell regulatory gene CTLA-4 polymorphism/haplotype association with autoimmune pancreatitis.
BACKGROUND Autoimmune pancreatitis (AIP) is a distinct disease entity of chronic pancreatitis. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a key negative regulator of the T-cell immune response, and its gene is highly polymorphic. Many positive associations between cytotoxic T-lymphocyte-associated protein 4 (CTLA4) single-nucleotide polymorphisms and various autoimmune diseases hav...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2005
ISSN: 0014-2980,1521-4141
DOI: 10.1002/eji.200526168